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Circadia Cyto-Comm Revitalizing Serum

Name: Circadia Cyto-Comm Revitalizing Serum
Brand: Circadia
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Circadia Cyto-Comm Revitalizing Serum

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Circadia · Professional Serum · Authorized Retailer · 0.5 oz

Cyto-Comm
Revitalizing Serum

DermCom + Progeline + LuShield + Tripeptide-38 — cell communication for repair, resilience & youth.

A professional-grade serum that helps skin cells communicate more effectively — supporting repair, deep hydration, and protection while visibly reducing early signs of aging and strengthening a compromised barrier. 0.5 oz / 15 mL.

DermCom Progeline LuShield Tripeptide-38 D-Ribose 0.5 oz / 15 mL

AM/PMDaily Use

AllSkin Types

5+Clinical Actives

A.G.E.Glycation Defense

Cell Communication Revitalizing Serum

Helps Skin Cells Communicate Better to Repair,
Hydrate, and Protect from Within.

Circadia Cyto-Comm Revitalizing Serum is a professional-grade treatment built around the principle of improving cellular communication — the biological process by which skin cells signal each other to repair damage, produce structural proteins, and maintain optimal function. DermCom (Crocus Chrysanthus Bulb Extract) improves epidermal communication to boost collagen and elastin production, stimulate growth factors, and renew resilience and firmness. Progeline (Trifluoroacetyl Tripeptide-2) reduces progerin synthesis, inhibits MMP and elastase activity, increases syndecan expression, and contracts collagen — collectively reducing sagging and wrinkles. DermalRx LuShield (Osmanthus Fragrans Flower Extract) detoxifies the skin from glycating agents and oxidants, protects biomolecules from the effects of glycation-induced inflammation, and prevents cell loss from Advanced Glycation End-products (A.G.E.s). Palmitoyl Tripeptide-38 stimulates the production of collagen I, III, and IV, as well as hyaluronic acid and fibronectin. D-Ribose promotes cell renewal and boosts skin vitality. Vita C (Aminopropyl Ascorbyl Phosphate) is a stabilized form of Vitamin C that stabilizes Vitamin E and provides antioxidant support. A special amino acid formulation — L-Glycine, L-Lysine, L-Proline, L-Valine, and L-Alanine — promotes collagen formation and cell signaling. Glycosaminoglycans (Sodium Hyaluronate) hydrate, lock in moisture, and support elasticity.

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DermCom

Epidermal communication — collagen & elastin

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Progeline

MMP inhibitor — reduces sagging & wrinkles

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LuShield

A.G.E. defense — anti-glycation protection

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Authorized Retailer

100% authentic Circadia — guaranteed

Key Actives

The Science of Cellular Communication

Cell Communicator

DermCom

Crocus Chrysanthus Bulb Extract — improves epidermal communication pathways to boost collagen and elastin production, stimulate growth factors, and renew skin resilience and firmness from within.

Anti-Aging Peptide

Progeline

Trifluoroacetyl Tripeptide-2 — reduces progerin synthesis, inhibits MMP and elastase activity, increases syndecan expression, and contracts collagen to visibly reduce sagging, wrinkles, and other signs of chronological aging.

Glycation Defense

DermalRx LuShield

Osmanthus Fragrans Flower Extract — detoxifies skin from glycating agents and oxidants, protects against glycation-induced inflammation, and prevents cell loss from Advanced Glycation End-products (A.G.E.s) and elevated sugar levels.

Collagen Stimulator

Palmitoyl Tripeptide-38

A signal peptide that stimulates the synthesis of collagen I, III, and IV, hyaluronic acid, and fibronectin — key structural proteins that support skin firmness, smoothness, and long-term elasticity.

Cellular Energizer

D-Ribose

A naturally occurring sugar that plays a central role in cellular energy production (ATP synthesis). In skincare, D-Ribose promotes cell renewal and boosts overall skin vitality and metabolic function.

Stabilized Vitamin C

Vita C (Aminopropyl Ascorbyl Phosphate)

A stabilized form of Vitamin C that is water-soluble and highly bioavailable. Stabilizes Vitamin E, acts as a broad antioxidant, and supports collagen synthesis — contributing to skin brightness and structural integrity.

Benefits

What It Does

Repair & Resilience

DermCom and Palmitoyl Tripeptide-38 improve cell communication and stimulate collagen and elastin to restore firmness, bounce, and skin resilience.

Hydration & Barrier

Glycosaminoglycans (Sodium Hyaluronate) and the amino acid complex lock in moisture and support a strengthened, healthier skin barrier for all skin types.

Anti-Aging Defense

Progeline reduces sagging and wrinkles while LuShield defends against glycation — two of the key biological drivers of skin aging — for comprehensive, multi-pathway protection.

Directions

How to Use

Morning and evening on clean skin, before moisturizer.

1

Cleanse

Cleanse skin thoroughly in the morning and evening. Pat dry. Cyto-Comm Serum is most effective when applied directly to clean, bare skin.

2

Apply Serum

Apply a few drops to fingertips and gently massage into the face and neck until fully absorbed. Allow 60 seconds for absorption before the next step.

3

Follow With Moisturizer

Follow with your moisturizer and SPF in the morning. In the evening, follow with a corrective lotion such as Circadia Glyco-Guard both morning and night for enhanced results.

Formulation

Ingredients

Key Actives

DermCom (Crocus Chrysanthus Bulb Extract) — improves epidermal communication; boosts collagen and elastin production; stimulates growth factors; renews resilience and firmness.

Progeline (Trifluoroacetyl Tripeptide-2) — reduces progerin synthesis; MMP and elastase inhibitor; increases syndecan; contracts collagen; reduces sagging and wrinkles.

DermalRx LuShield (Osmanthus Fragrans Flower Extract) — detoxifies from glycating agents and oxidants; protects against glycation-induced inflammation; prevents A.G.E.-related cell loss.

Palmitoyl Tripeptide-38 (MATRIXYL synthe'6) — stimulates collagen I, III, IV, hyaluronic acid, and fibronectin production.

D-Ribose — promotes cell renewal; boosts skin vitality and metabolic function.

Vita C / Aminopropyl Ascorbyl Phosphate — stabilized Vitamin C; antioxidant; stabilizes Vitamin E; supports collagen synthesis.

Glycosaminoglycans / Sodium Hyaluronate — hydrates, locks in moisture, supports elasticity.

Amino Acid Complex (L-Glycine, L-Lysine, L-Proline, L-Valine, L-Alanine) — promotes collagen formation and cell signaling.

Full Ingredient List

Aqua/Water, Aminopropyl Ascorbyl Phosphate, Pentylene Glycol, Sodium Hyaluronate, Acacia Senegal Gum, Glycerin, Osmanthus Fragrans Flower Extract, Caprylyl Glycol, Tetrasodium EDTA, Phenoxyethanol, Trifluoroacetyl Tripeptide-2, Dextran, Valine, Proline, Glycine, Alanine, Lysine Hydrochloride, Crocus Chrysanthus Bulb Extract, Sodium Hydroxide, Hexylene Glycol, Propanediol, Sodium Metabisulfite.

Specifications

Product Details

Brand	Circadia by Dr. Pugliese
Size	0.5 oz / 15 mL retail
Product Type	Cell communication revitalizing serum
Skin Types	All Skin Types · Dehydrated · Sensitive / Compromised Barrier · Early Aging
Application	Morning and evening on clean skin; apply a few drops, massage into face and neck; follow with moisturizer and SPF (AM) or corrective lotion (AM & PM)
Key Actives	DermCom (Crocus Chrysanthus), Progeline (Trifluoroacetyl Tripeptide-2), DermalRx LuShield (Osmanthus Fragrans), Palmitoyl Tripeptide-38, D-Ribose, Vita C (Aminopropyl Ascorbyl Phosphate), Sodium Hyaluronate, Amino Acid Complex
Sold By	Auréa Beauty — Authorized Circadia Retailer (myaurea.beauty)

FAQ

Common Questions

Everything you need to know about Circadia Cyto-Comm Revitalizing Serum.

What is Circadia Cyto-Comm Revitalizing Serum?

A professional-grade serum that improves skin cell communication to support repair, hydration, and protection. Formulated with DermCom, Progeline, DermalRx LuShield, Palmitoyl Tripeptide-38, D-Ribose, and stabilized Vitamin C. 0.5 oz / 15 mL retail.

What is DermCom?

DermCom (Crocus Chrysanthus Bulb Extract) improves epidermal communication pathways to boost collagen and elastin production, stimulate growth factors, and renew skin resilience and firmness — addressing the cellular signaling breakdown that contributes to aging.

What is Progeline?

Progeline (Trifluoroacetyl Tripeptide-2) is an advanced anti-aging peptide that reduces progerin synthesis, inhibits MMP and elastase activity, increases syndecan, and contracts collagen — reducing visible signs of aging including sagging and wrinkles.

What is DermalRx LuShield?

DermalRx LuShield (Osmanthus Fragrans Flower Extract) detoxifies the skin from glycating agents and oxidants, protects biomolecules from glycation-induced inflammation, and prevents cell loss from Advanced Glycation End-products (A.G.E.s) — a key mechanism of skin aging.

What does Palmitoyl Tripeptide-38 do?

Palmitoyl Tripeptide-38 stimulates the synthesis of collagen I, III, and IV, as well as hyaluronic acid and fibronectin — key structural components that support skin firmness, elasticity, and hydration.

How do I use Circadia Cyto-Comm Revitalizing Serum?

Apply a few drops to clean skin morning and evening. Gently massage into the face and neck until fully absorbed. Follow with moisturizer and SPF in the morning, or a corrective lotion such as Glyco-Guard both morning and night.

Is Auréa Beauty an authorized Circadia retailer?

Yes. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer. All Circadia products are 100% authentic and backed by the brand's quality guarantee.

Ideal For

Who Is This For?

All Skin Types Dehydrated Skin Sensitive Skin Compromised Barrier Early Aging Loss of Firmness Glycation Damage Daily Repair Serum

For external use only. Avoid direct contact with eyes. If irritation occurs, discontinue use and consult a healthcare professional. Keep out of reach of children. Circadia products are developed for professional skincare use. Sold exclusively through authorized Circadia retailers. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer.

Payment Protection + Pay Later Options
Easy 30-Day Returns

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GLOWING SKIN IS ALWAYS IN

Luxury That Loves Your Skin, Your Hair, and the Planet

Auréa Beauty stands for more than visible results—we stand for responsibility. We believe in derm-developed, cruelty-free, and sustainably sourced formulas.

✔ We're proudly woman-owned: created with heart, honesty, and intention.

✔ Real, medical-grade skincare and haircare you can actually trust—without fluff and false promises.

✔ We make self-care simple, personal, and powerful.

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Questions? We've got you!

Shipping & Returns

We ship within the US only.

1. Economy Shipping costs $11.99 and takes 5–8 business days.

2. Express Shipping costs $24.99 and takes 2–3 business days.

Yes, we accept returns within 30 days. Terms and conditions apply, see them here.

We accept a variety of payment methods including major credit cards (Visa, Mastercard, etc.), plus alternative payment options like Apple Pay, Shop Pay, and PayPal.

Once your order is placed and shipped, you will receive a confirmation email. Use the tracking information provided to follow delivery.

If you're missing tracking or have any concerns, please reach out to our customer support.

Products & Quality

Auréa Beauty is a proudly woman-owned online store offering premium, medical-grade skincare and advanced beauty devices.

All products are guaranteed authentic, dermatologist-recommended, sourced directly from trusted brands like Bio-Therapeutic, Circadia, GlyMed Plus, and TiZO.