What is Circadia Revita-Cyte Complex Revitalizing Lotion?

A rejuvenating Vitamin A-alternative lotion for aging, dull, and tired skin. Key actives include EUK-134 (antioxidant enzyme mimic), Pepha-ctive (microalgae ATP booster), Thymulen 4 (Acetyl Tetrapeptide-2), Revitalin PF, Oat Beta Glucan, Exo-T, and Chronocyclin. Evening use after cleanser and serum.

EUK-134 (Ethylbisiminomethylguaiacol Manganese Chloride) is a synthetic mimic of both superoxide dismutase and catalase enzymes. It scavenges superoxide radicals, eliminates hydrogen peroxide, transforms reactive oxygen species into water and oxygen, and reduces free radical DNA and lipid damage in the skin — providing comprehensive enzymatic antioxidant protection.

Pepha-ctive is a microalgae extract (Algae Extract) that protects and stimulates mitochondria by increasing ATP (cellular energy) levels and improves skin radiance. By boosting mitochondrial activity, it helps energize skin cells and supports healthy metabolic function that declines with aging.

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Circadia Revita-Cyte Complex Revitalizing Lotion

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Circadia Revita-Cyte Complex Revitalizing Lotion

Name: Circadia Revita-Cyte Complex Revitalizing Lotion
Brand: Circadia
Availability: InStock

$112.00

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Circadia Revita-Cyte Complex Revitalizing Lotion

$112.00

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Circadia · Vitamin A-Alternative Lotion · Authorized Retailer · Evening Use

Revita-Cyte Complex
Revitalizing Lotion

EUK-134 + Pepha-ctive + Thymulen 4 + Chronocyclin — firms, energizes, and protects without retinol.

A rejuvenating Vitamin A-alternative evening lotion that delivers comprehensive anti-aging support — neutralizing reactive oxygen species, boosting mitochondrial energy, stimulating cell regeneration, and optimizing the skin's circadian renewal rhythms.

EUK-134Pepha-ctiveThymulen 4ChronocyclinRevitalin PFRetinol-Free

PMEvening Use

ATPMitochondrial Energy

ROSFree Radical Defense

AllSkin Types

Vitamin A-Alternative Revitalizing Lotion

Firms, Smooths, and Energizes Aging Skin
Without Retinol — Through Enzymatic Science.

Circadia Revita-Cyte Complex Revitalizing Lotion is a professional-grade evening lotion that delivers comprehensive anti-aging regeneration through enzymatic antioxidant science, mitochondrial support, and immune-boosting peptides — making it an ideal alternative for those who cannot tolerate retinoids. EUK-134 (Ethylbisiminomethylguaiacol Manganese Chloride) is a synthetic mimic of both superoxide dismutase and catalase enzymes — scavenging superoxide radicals, eliminating hydrogen peroxide, transforming reactive oxygen species to water and oxygen, and reducing DNA and lipid free radical damage. Pepha-ctive (Microalgae/Algae Extract) protects and stimulates mitochondria by increasing ATP levels and improves skin radiance. Revitalin PF (purified mitochondrial and cytoplasmic fraction from yeast) stimulates cell respiratory activity, revitalizes skin metabolism, and strengthens self-protection mechanisms. Thymulen 4 (Acetyl Tetrapeptide-2) is a biomimetic of thymopoietin that boosts skin regeneration and reinforces cutaneous immune defenses for improved firmness and resilience. Exo-T (Vibrio Alginolyticus Ferment Filtrate) stimulates desquamation and transglutaminase expression for improved texture and tensile strength. Chronocyclin (Chronopeptide) enhances circadian gene expression, optimizes cell defenses and renewal activities, and supports Vitamin D transformation in sync with the skin's biological clock. Oat Beta Glucan activates the skin's natural repair system. Edelweiss Meristem Extract (Leontopodium Alpinum) provides additional antioxidant support.

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EUK-134

SOD + catalase mimic — ROS neutralization

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Pepha-ctive

Microalgae — mitochondrial ATP booster

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Thymulen 4

Thymopoietin mimetic — skin immunity

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Authorized Retailer

100% authentic Circadia — guaranteed

Key Actives

Enzymatic Anti-Aging Science Without Retinol

Dual Enzyme Mimic

EUK-134

Ethylbisiminomethylguaiacol Manganese Chloride — a synthetic mimic of both superoxide dismutase (SOD) and catalase. Scavenges superoxide, eliminates hydrogen peroxide, transforms reactive oxygen species to harmless water and oxygen, and reduces free radical DNA and lipid damage.

Mitochondrial Energizer

Pepha-ctive

Microalgae/Algae Extract — protects and stimulates mitochondria by increasing ATP (cellular energy) production. Improves skin radiance and supports the metabolic cellular activity that declines with chronological aging.

Immune-Boosting Peptide

Thymulen 4 (Acetyl Tetrapeptide-2)

A biomimetic of thymopoietin — the thymus-derived hormone regulating immune function. Boosts skin regeneration and reinforces cutaneous immune defenses for improved firmness, resilience, and self-protection capacity.

Circadian Optimizer

Chronocyclin

Chronopeptide — enhances the expression of circadian (biological clock) genes, optimizes cellular defense and renewal activities, and supports Vitamin D transformation. Works in harmony with the skin's natural day-night repair rhythms.

Cellular Respirator

Revitalin PF

Purified mitochondrial and cytoplasmic fraction from yeast — stimulates cell respiratory activity and cell turnover, revitalizes skin metabolism, and strengthens the skin's self-protection mechanisms for enhanced resilience.

Texture Renewer

Exo-T

Vibrio Alginolyticus Ferment Filtrate — Polynesian atoll exopolysaccharide that stimulates desquamation, keratinocyte differentiation, and transglutaminase expression to regenerate skin and improve tensile strength, smoothness, and texture.

Benefits

What It Does

Environmental Defense

EUK-134 provides unparalleled enzymatic ROS neutralization — protecting against the oxidative and UV-induced damage that accelerates skin aging, without the photosensitivity of retinoids.

Regeneration & Firmness

Thymulen 4 reinforces skin immunity and regeneration. Revitalin PF stimulates cell turnover. Exo-T improves texture and tensile strength — collectively delivering firmer, smoother skin.

Energy & Radiance

Pepha-ctive boosts mitochondrial ATP levels and Chronocyclin optimizes circadian gene expression — restoring the cellular energy and biological rhythm that dull, aging skin needs to renew.

Directions

How to Use

Evening after cleanser and serum. No photosensitivity — no mandatory SPF increase required.

1

Cleanse & Apply Serum

Cleanse thoroughly in the evening and apply any targeted serums first. Revita-Cyte Complex is applied as the final moisturizing step in your evening routine.

2

Apply

Dispense 1–2 pumps onto fingertips and apply over the face and neck. Avoid contact with eyes. Unlike retinol, this formula does not cause photosensitivity — ideal for those seeking retinol-equivalent results without the restrictions.

Formulation

Ingredients

Key Actives

EUK-134 (Ethylbisiminomethylguaiacol Manganese Chloride) — SOD + catalase mimic; scavenges superoxide; eliminates hydrogen peroxide; transforms ROS to water/oxygen; reduces DNA and lipid damage.

Pepha-ctive (Algae Extract) — microalgae; stimulates mitochondria; increases ATP levels; improves skin radiance.

Revitalin PF (Glycoproteins) — purified mitochondrial and cytoplasmic fraction from yeast; stimulates cell respiratory activity; revitalizes skin metabolism.

Thymulen 4 (Acetyl Tetrapeptide-2) — thymopoietin biomimetic; boosts skin regeneration; reinforces cutaneous immune defenses; improves firmness.

Exo-T (Vibrio Alginolyticus Ferment Filtrate) — Polynesian exopolysaccharide; stimulates desquamation and transglutaminase; improves tensile strength, smoothness, and texture.

Chronocyclin (Glutamylamidoethyl Imidazole) — Chronopeptide; anti-aging; enhances circadian gene expression; optimizes cell defenses and renewal; Vitamin D transformation.

Oat Beta Glucan (Beta-Glucan) — immune stimulant; activates natural skin repair system.

Edelweiss Meristem (Leontopodium Alpinum Meristem Cell Culture) — antioxidant; anti-collagenase; anti-hyaluronidase.

Tocopherol (Vitamin E) — fat-soluble antioxidant; protects cellular membranes from free radicals.

Full Ingredient List

Aqua/Water, PPG-15 Stearyl Ether, Polysilicone-11, Glycerin, Squalane, Carbomer, Polysorbate 20, Butylene Glycol, Panthenol, Allantoin, Tocopheryl Acetate, Hydroxyethylpiperazine Ethane Sulfonic Acid, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Leontopodium Alpinum Meristem Cell Culture, Caprylyl Glycol, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Vibrio Alginolyticus Ferment Filtrate, Bisabolol, Phenoxyethanol, Laureth-12, Palmitoyl Tripeptide-38, Algae Extract, Acetyl Tetrapeptide-2, Glutamic Acid, Glycoproteins, Dextran, Dimethylmethoxy Chromanol, Ethylbisiminomethylguaiacol Manganese Chloride, Hydroxypropyl Cyclodextrin, Cananga Odorata Flower Extract, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate, Avena Sativa Kernel Extract, Valine, Threonine, Xanthan Gum, Tetrasodium EDTA, Beta-Glucan, Glutamylamidoethyl Imidazole, Sodium Metabisulfite, Sorbic Acid, Linalool.

Specifications

Product Details

Brand	Circadia by Dr. Pugliese
Product Type	Vitamin A-alternative rejuvenating evening lotion
Skin Types	All Skin Types · Aging · Dull or Tired Skin · Post-SWiCH Support
Application	Evening after cleanser and serum; dispense 1–2 pumps; apply over face and neck; avoid eye contact
Key Actives	EUK-134, Pepha-ctive (Microalgae), Thymulen 4 (Acetyl Tetrapeptide-2), Revitalin PF, Oat Beta Glucan, Exo-T (Vibrio Alginolyticus), Chronocyclin, Edelweiss Meristem, Tocopherol
Contains	Linalool, Cananga Odorata (Ylang Ylang) Flower Extract — patch test recommended for fragrance sensitivities.
Retinol-Free	Yes — does not contain retinol or retinoids; no photosensitivity; no mandatory SPF increase required.
Sold By	Auréa Beauty — Authorized Circadia Retailer (myaurea.beauty)

FAQ

Common Questions

Everything you need to know about Circadia Revita-Cyte Complex Revitalizing Lotion.

What is Circadia Revita-Cyte Complex?

A Vitamin A-alternative rejuvenating evening lotion for aging and dull skin. Key actives: EUK-134 (dual enzyme mimic), Pepha-ctive (mitochondrial ATP booster), Thymulen 4 (Acetyl Tetrapeptide-2), Chronocyclin (circadian peptide), Revitalin PF, Exo-T, and Oat Beta Glucan. Evening use only; retinol-free.

What is EUK-134?

EUK-134 is a synthetic mimic of both superoxide dismutase and catalase — two of the body's primary antioxidant enzymes. It scavenges superoxide radicals, eliminates hydrogen peroxide, converts reactive oxygen species to harmless water and oxygen, and protects against DNA and lipid damage in the skin.

What is Pepha-ctive?

Pepha-ctive is a microalgae extract that protects and stimulates mitochondria by increasing ATP (cellular energy) levels and improves skin radiance — supporting the metabolic cellular activity that declines with aging.

What is Thymulen 4?

Thymulen 4 (Acetyl Tetrapeptide-2) is a biomimetic of thymopoietin — a hormone from the thymus gland that regulates immune function. It boosts skin regeneration and reinforces cutaneous immune defenses for improved firmness and resilience.

Why is this called a Vitamin A alternative?

Revita-Cyte delivers comparable cell renewal, regeneration, and anti-aging support to retinol — through enzymatic antioxidants, mitochondrial activation, and immune-boosting peptides — without retinol's associated photosensitivity or irritation risk. Ideal for those who cannot tolerate retinoids.

What is Chronocyclin?

Chronocyclin (Glutamylamidoethyl Imidazole) is a Chronopeptide that enhances the expression of circadian genes, optimizes cell defense and renewal activities, and supports Vitamin D transformation — working in harmony with the skin's natural biological clock.

How do I use Revita-Cyte Complex?

Evening after cleanser and serum, dispense 1–2 pumps onto fingertips and apply over face and neck. Avoid eye contact. Unlike retinol products, no photosensitivity protocol is required.

Is Auréa Beauty an authorized Circadia retailer?

Yes. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer. All products are 100% authentic and backed by the brand's quality guarantee.

Ideal For

Who Is This For?

All Skin TypesAging SkinDull or Tired SkinPost-SWiCH SupportRetinol-SensitiveLoss of FirmnessEnvironmental DamageVitamin A Alternative

For external use only. Avoid contact with eyes. Contains Linalool and Cananga Odorata Flower Extract — patch test recommended for fragrance sensitivities. If irritation occurs, discontinue use and consult a healthcare professional. Keep out of reach of children. Sold exclusively through authorized Circadia retailers. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer.

Payment Protection + Pay Later Options
Easy 30-Day Returns

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Auréa Beauty stands for more than visible results—we stand for responsibility. We believe in derm-developed, cruelty-free, and sustainably sourced formulas.

✔ We're proudly woman-owned: created with heart, honesty, and intention.

✔ Real, medical-grade skincare and haircare you can actually trust—without fluff and false promises.

✔ We make self-care simple, personal, and powerful.

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Questions? We've got you!

Shipping & Returns

We ship within the US only.

1. Economy Shipping costs $11.99 and takes 5–8 business days.

2. Express Shipping costs $24.99 and takes 2–3 business days.

Yes, we accept returns within 30 days. Terms and conditions apply, see them here.

We accept a variety of payment methods including major credit cards (Visa, Mastercard, etc.), plus alternative payment options like Apple Pay, Shop Pay, and PayPal.

Once your order is placed and shipped, you will receive a confirmation email. Use the tracking information provided to follow delivery.

If you're missing tracking or have any concerns, please reach out to our customer support.

Products & Quality

Auréa Beauty is a proudly woman-owned online store offering premium, medical-grade skincare and advanced beauty devices.

All products are guaranteed authentic, dermatologist-recommended, sourced directly from trusted brands like Bio-Therapeutic, Circadia, GlyMed Plus, and TiZO.