Inyline (Acetyl Hexapeptide-30) is a peptide that reduces the depth of wrinkles caused by contraction of facial expression muscles — without freezing movement. It works in combination with Snap-8 to address expression lines from multiple angles.

Snap-8 (Acetyl Octapeptide-3) is an eight-amino-acid peptide that modulates the SNARE complex — the protein mechanism responsible for neuromuscular communication that drives repetitive facial muscle contractions. It reduces the depth of expression-driven wrinkles.

What Matrixyl variants does this serum contain?

Myo-Cyte Plus contains three generations of Matrixyl: original Matrixyl (Palmitoyl Oligopeptide / Palmitoyl Pentapeptide-4) which stimulates collagen and elastin synthesis; Matrixyl 3000 (Palmitoyl Pentapeptide-3) which helps repair damaged tissues; and Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) which boosts six major matrix proteins including collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5.

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Circadia Myo-Cyte Plus Anti-Wrinkle Serum

Product label: % Sale

Circadia Myo-Cyte Plus Anti-Wrinkle Serum

Name: Circadia Myo-Cyte Plus Anti-Wrinkle Serum
Brand: Circadia
Availability: InStock

$160.00

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Circadia Myo-Cyte Plus Anti-Wrinkle Serum

$160.00

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Circadia · Professional Anti-Wrinkle Serum · Authorized Retailer · 0.5 oz

Myo-Cyte Plus
Anti-Wrinkle Serum

Inyline + Snap-8 + Triple Matrixyl + Passion Flower — softens expression lines while preserving natural movement.

A professional-grade peptide serum that delivers immediate softening of expression lines and long-term collagen stimulation — using muscle-relaxing actives that ease facial micro-tension without freezing movement. 0.5 oz / 15 mL.

InylineSnap-8Triple MatrixylPassion FlowerHyaluronic Acid0.5 oz / 15 mL

AM/PMDaily Use

3×Matrixyl Generations

NoFreezing Effect

6+Peptide Actives

Advanced Peptide Anti-Wrinkle Serum

Softens Expression Lines Immediately.
Rebuilds Collagen Long-Term.

Circadia Myo-Cyte Plus Anti-Wrinkle Serum is a multi-peptide treatment that addresses fine lines and deep wrinkles from two complementary directions: immediate muscle-relaxing action that softens expression lines, and sustained collagen stimulation that rebuilds skin structure. Inyline (Acetyl Hexapeptide-30) and Snap-8 (Acetyl Octapeptide-3) modulate neuromuscular signaling to reduce the depth of wrinkles caused by repetitive facial muscle contractions — without freezing expression. Dipeptide Diaminobutyroyl Benzylamide Diacetate mimics a natural muscle relaxer to ease micro-tension. Passion Flower Extract (Passiflora Incarnata) contains three powerful natural muscle relaxants effective in smoothing wrinkled skin. Three generations of Matrixyl provide collagen-stimulating support: original Matrixyl (Palmitoyl Oligopeptide + Palmitoyl Pentapeptide-4) stimulates collagen and elastin similarly to retinol; Matrixyl 3000 (Palmitoyl Pentapeptide-3) helps repair damaged tissues; and Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) boosts six major matrix proteins for comprehensive structural rebuilding. Sodium Hyaluronate deeply hydrates and plumps to reduce the visible appearance of fine lines. A complete amino acid complex — L-Proline, L-Glycine, L-Carnosine, L-Threonine — supports collagen fiber formation and provides anti-glycation protection.

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Inyline + Snap-8

Peptide muscle modulation — no freezing

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Triple Matrixyl

3 generations — collagen & elastin rebuilding

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Passion Flower

3 natural muscle relaxants — smooths wrinkles

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Authorized Retailer

100% authentic Circadia — guaranteed

Key Actives

The Peptide Science Behind Smoother Skin

Expression Line Relaxer

Inyline (Acetyl Hexapeptide-30)

Modulates the contraction signals in facial expression muscles to reduce the depth of expression-driven wrinkles — without blocking movement. Works synergistically with Snap-8 for a comprehensive muscle-relaxing approach.

SNARE Complex Modulator

Snap-8 (Acetyl Octapeptide-3)

An eight-amino-acid peptide that modulates the SNARE complex — the protein machinery controlling neuromuscular communication. Reduces depth of expression-driven wrinkles by softening repetitive muscle micro-contractions.

Natural Muscle Relaxant

Passion Flower Extract

Passiflora Incarnata Flower Extract — contains three documented natural muscle-relaxing compounds effective at smoothing wrinkled skin. Provides botanical support to the formula's peptide-based muscle relaxation strategy.

Collagen Stimulator (Gen 1)

Matrixyl

Palmitoyl Oligopeptide + Palmitoyl Pentapeptide-4 — the original Matrixyl; stimulates collagen and elastin synthesis in a manner similar to retinol, without irritation. Also assists in repairing damaged tissue at the matrix level.

Matrix Rebuilder (Gen 3)

Matrixyl Synthe'6

Palmitoyl Tripeptide-38 — third-generation Matrixyl that boosts collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5. Rebuilds the full dermal-epidermal junction for comprehensive long-term wrinkle reduction.

Plumping Hydrator

Sodium Hyaluronate

Hyaluronic Acid — a natural muscle relaxant with anti-inflammatory properties that hydrates skin by binding and retaining moisture. Immediately plumps and softens fine lines for a visible smoothing effect alongside the peptide actives.

Benefits

What It Does

Expression Lines

Inyline, Snap-8, and Passion Flower Extract modulate muscle micro-contractions to visibly soften crow's feet, forehead lines, and frown lines — without freezing expression.

Firmness & Elasticity

Triple Matrixyl stimulates collagen and elastin production across three generations of peptide technology — improving skin firmness, bounce, and structural integrity over time.

Hydration & Plumping

Sodium Hyaluronate deeply hydrates and plumps while the amino acid complex (L-Proline, L-Glycine, L-Carnosine) supports collagen fiber formation and provides anti-glycation protection.

Directions

How to Use

Morning and evening on clean skin before moisturizer.

1

Cleanse

Cleanse thoroughly morning and evening. Pat dry. Myo-Cyte Plus is most effective when applied directly to clean, bare skin before any other products.

2

Apply & Massage

Apply a few drops to fingertips and massage into the face and neck, focusing on areas with expression lines — forehead, crow's feet, nasolabial folds, lip lines. Allow 60 seconds to absorb.

3

Follow With Moisturizer

Follow with your moisturizer. In the morning, finish with broad-spectrum SPF. The peptides in this serum work continuously — consistent twice-daily use delivers cumulative long-term results.

Formulation

Ingredients

Key Actives

Inyline (Acetyl Hexapeptide-30) — reduces depth of expression-driven wrinkles; modulates facial muscle contraction signals.

Snap-8 (Acetyl Octapeptide-3) — modulates SNARE complex; reduces depth of expression wrinkles.

Matrixyl (Palmitoyl Oligopeptide + Palmitoyl Pentapeptide-4) — stimulates collagen and elastin; retinol-like without irritation; repairs damaged tissue.

Matrixyl 3000 (Palmitoyl Pentapeptide-3) — repairs damaged tissue; collagen stimulation.

Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) — boosts collagen I, III, IV, fibronectin, hyaluronic acid, laminin 5.

Sodium Hyaluronate — deep hydration; plumps fine lines; natural anti-inflammatory.

Passion Flower Extract (Passiflora Incarnata) — three natural muscle relaxants; smooths wrinkled skin.

Amino Acid Complex (L-Proline, L-Glycine, L-Carnosine, L-Threonine) — collagen fiber formation; anti-glycation (Carnosine); antioxidant stabilization (Threonine).

Full Ingredient List

Aqua/Water, Glycerin, Butylene Glycol, Ethoxydiglycol, Sodium Hyaluronate, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Magnesium Ascorbyl Phosphate, Arginine, Carnosine, Acetyl Octapeptide-3, Proline, Glycine, Threonine, Rosmarinus Officinalis Leaf Extract, Chamomilla Recutita Flower Extract, Passiflora Incarnata Flower Extract, Acetyl Hexapeptide-30, Caprylyl Glycol, Carbomer, Tetrasodium EDTA, Phenoxyethanol, Polysorbate 20, Hexylene Glycol.

Specifications

Product Details

Brand	Circadia by Dr. Pugliese
Size	0.5 oz / 15 mL retail
Product Type	Multi-peptide anti-wrinkle serum
Skin Types	Aging · Fine Lines / Deep Wrinkles · Loss of Firmness
Application	Morning and evening on clean skin; apply a few drops; massage into face and neck focusing on expression lines; follow with moisturizer and SPF (AM)
Key Actives	Inyline (Acetyl Hexapeptide-30), Snap-8 (Acetyl Octapeptide-3), Matrixyl (Palmitoyl Oligopeptide), Matrixyl 3000 (Palmitoyl Pentapeptide-3 / Tetrapeptide-7), Matrixyl Synthe'6 (Palmitoyl Tripeptide-38), Sodium Hyaluronate, Passiflora Incarnata Extract
Sold By	Auréa Beauty — Authorized Circadia Retailer (myaurea.beauty)

FAQ

Common Questions

Everything you need to know about Circadia Myo-Cyte Plus Anti-Wrinkle Serum.

What is Circadia Myo-Cyte Plus Anti-Wrinkle Serum?

A professional peptide serum delivering immediate wrinkle softening and long-term collagen stimulation. Key actives: Inyline (Acetyl Hexapeptide-30), Snap-8 (Acetyl Octapeptide-3), triple Matrixyl complex, Sodium Hyaluronate, and Passion Flower Extract. 0.5 oz / 15 mL.

What is Inyline?

Inyline (Acetyl Hexapeptide-30) is a peptide that reduces the depth of expression-driven wrinkles by modulating facial muscle contraction signals — softening crow's feet, forehead lines, and frown lines without freezing natural movement.

What is Snap-8?

Snap-8 (Acetyl Octapeptide-3) is an eight-amino-acid peptide that modulates the SNARE complex — the protein mechanism controlling neuromuscular communication that drives repetitive facial muscle contractions responsible for expression wrinkles.

Will this freeze my facial expressions?

No. Myo-Cyte Plus modulates rather than blocks muscle activity. Inyline, Snap-8, and Passion Flower Extract reduce micro-tension to soften expression lines while preserving full natural facial movement and expression.

What Matrixyl versions does this contain?

Three generations: original Matrixyl (Palmitoyl Oligopeptide + Pentapeptide-4), Matrixyl 3000 (Palmitoyl Pentapeptide-3), and Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) — providing comprehensive collagen, elastin, hyaluronic acid, and matrix protein stimulation.

How do I use Myo-Cyte Plus?

Apply a few drops to clean skin morning and evening. Massage into the face and neck, focusing on expression lines. Follow with moisturizer and SPF in the morning.

Is Auréa Beauty an authorized Circadia retailer?

Yes. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer. All products are 100% authentic and backed by the brand's quality guarantee.

Ideal For

Who Is This For?

Aging SkinExpression LinesCrow's FeetDeep WrinklesLoss of FirmnessForehead LinesPeptide Alternative to BotoxDaily Anti-Wrinkle Serum

For external use only. Avoid contact with eyes. If irritation occurs, discontinue use and consult a healthcare professional. Keep out of reach of children. Sold exclusively through authorized Circadia retailers. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer.

Payment Protection + Pay Later Options
Easy 30-Day Returns

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GLOWING SKIN IS ALWAYS IN

Luxury That Loves Your Skin, Your Hair, and the Planet

Auréa Beauty stands for more than visible results—we stand for responsibility. We believe in derm-developed, cruelty-free, and sustainably sourced formulas.

✔ We're proudly woman-owned: created with heart, honesty, and intention.

✔ Real, medical-grade skincare and haircare you can actually trust—without fluff and false promises.

✔ We make self-care simple, personal, and powerful.

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Questions? We've got you!

Shipping & Returns

We ship within the US only.

1. Economy Shipping costs $11.99 and takes 5–8 business days.

2. Express Shipping costs $24.99 and takes 2–3 business days.

Yes, we accept returns within 30 days. Terms and conditions apply, see them here.

We accept a variety of payment methods including major credit cards (Visa, Mastercard, etc.), plus alternative payment options like Apple Pay, Shop Pay, and PayPal.

Once your order is placed and shipped, you will receive a confirmation email. Use the tracking information provided to follow delivery.

If you're missing tracking or have any concerns, please reach out to our customer support.

Products & Quality

Auréa Beauty is a proudly woman-owned online store offering premium, medical-grade skincare and advanced beauty devices.

All products are guaranteed authentic, dermatologist-recommended, sourced directly from trusted brands like Bio-Therapeutic, Circadia, GlyMed Plus, and TiZO.