BV-OSC (Tetrahexyldecyl Ascorbate) is a highly stable, oil-soluble Vitamin C ester that penetrates deeply into the skin. It reduces melanin synthesis for improved tone and provides antioxidant protection without the instability issues of water-soluble Vitamin C forms.

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Circadia Phito-pep 1.6 Antioxidant Lotion

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Circadia Phito-pep 1.6 Antioxidant Lotion

Name: Circadia Phito-Pep 1.6 Antioxidant Lotion
Brand: Circadia
Availability: InStock

$62.00

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Circadia Phito-pep 1.6 Antioxidant Lotion

$62.00

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Circadia · Anti-Aging Moisturizer · Authorized Retailer

Phito-Pep 1.6
Antioxidant Lotion

BV-OSC + Matrixyl Synthe'6 + Exo-T + Dismutin PF — hydrates, rebuilds collagen, and refines texture.

An advanced anti-aging moisturizer that deeply hydrates, boosts six key structural proteins, stimulates natural skin renewal, and defends against oxidative and DNA damage — for firmer, smoother, more radiant skin.

BV-OSC Vitamin CMatrixyl Synthe'6Exo-TDismutin PFPhormistim GPanthenol B5

AM/PMDaily Use

6Matrix Proteins Boosted

AllSkin Types

DNAProtection

Anti-Aging Antioxidant Moisturizer

Rebuilds Skin Structure from Within While Defending
Against Oxidative and DNA Damage.

Circadia Phito-Pep 1.6 Antioxidant Lotion is a professional-grade moisturizer built around a multi-active approach to aging: repairing the skin matrix, stimulating natural exfoliation, and providing layered antioxidant defense. Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) significantly increases synthesis of six major skin matrix components — collagen I, III, and IV, fibronectin, hyaluronic acid, and laminin 5 — rebuilding skin structure from within to smooth wrinkles and restore elasticity. BV-OSC (Tetrahexyldecyl Ascorbate) is a highly stable, oil-soluble Vitamin C ester that penetrates deeply to reduce melanin synthesis and deliver powerful antioxidant protection. Exo-T (Vibrio Alginolyticus Ferment Filtrate) is a Polynesian atoll-derived exopolysaccharide that stimulates desquamation, keratinocyte differentiation, and transglutaminase expression to regenerate skin and improve tensile strength, smoothness, and texture. Dismutin PF (Superoxide Dismutase) is yeast-derived SOD — a master antioxidant enzyme that neutralizes superoxide free radicals and protects cell membranes. Phormistim G (Phormidium Persicinum Extract) is a South African plankton extract that increases thioredoxin activity to reduce DNA damage. Everlasting-ECO (Helichrysum Stoechas Extract) is polyphenol-rich and anti-aging. Panthenol (Provitamin B5) regenerates and soothes.

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Matrixyl Synthe'6

6 matrix proteins — collagen, HA, laminin 5

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Exo-T

Polynesian microorganism — renewal & texture

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Dismutin PF (SOD)

Superoxide dismutase — cell membrane defense

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Authorized Retailer

100% authentic Circadia — guaranteed

Key Actives

Advanced Anti-Aging Technology in Every Drop

Collagen Matrix Booster

Matrixyl Synthe'6

Palmitoyl Tripeptide-38 — increases synthesis of collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5. Evens out skin relief and smooths wrinkles by rebuilding the matrix and dermal-epidermal junction from within.

Oil-Soluble Vitamin C

BV-OSC

Tetrahexyldecyl Ascorbate — a highly stable, lipid-soluble Vitamin C ester with deep skin penetration. Reduces melanin synthesis for improved tone while delivering potent antioxidant protection without oxidative instability.

Skin Renewal Exopolysaccharide

Exo-T

Vibrio Alginolyticus Ferment Filtrate — from microorganisms at Polynesian atoll rims. Stimulates desquamation, differentiation, and transglutaminase expression to regenerate skin and improve tensile strength, smoothness, and surface texture.

Antioxidant Enzyme

Dismutin PF (SOD)

Yeast-derived Superoxide Dismutase — the body's own primary antioxidant enzyme. Neutralizes superoxide free radicals, protects cell membranes from oxidative damage, and supports overall cellular defense.

DNA Protector

Phormistim G

Phormidium Persicinum Extract (South African plankton) combined with sea water. Increases thioredoxin activity — a key cellular defense mechanism — to reduce UV and oxidative DNA damage in skin cells.

Anti-Aging Botanical

Everlasting-ECO

Helichrysum Stoechas Extract — rich in polyphenols with documented anti-aging activity. Provides antioxidant support and complements the formula's broader cellular protection strategy.

Benefits

What It Does

Hydration & Barrier

Panthenol and hyaluronic acid production (stimulated by Matrixyl) deeply hydrate while restoring moisture balance and strengthening the skin barrier.

Collagen & Firmness

Matrixyl Synthe'6 boosts six key structural proteins to rebuild the skin matrix — visibly smoothing wrinkles and improving firmness and elasticity over time.

Tone & Texture

BV-OSC Vitamin C improves skin tone while Exo-T stimulates renewal for refined surface texture — together improving the overall quality and radiance of the complexion.

Directions

How to Use

Morning and evening after cleansing and serums.

1

Cleanse & Apply Serums

Cleanse thoroughly morning and evening. Apply any targeted serums first — Phito-Pep 1.6 is applied as the final moisturizing step.

2

Apply

Smooth over the face and neck, avoiding the eye area. Follow with SPF in the morning. Contains Parfum — patch test recommended for fragrance sensitivities.

Formulation

Ingredients

Key Actives

BV-OSC (Tetrahexyldecyl Ascorbate) — oil-soluble Vitamin C; highly stable; reduces melanin synthesis; antioxidant.

Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) — boosts collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5; smooths and rebuilds skin matrix.

Exo-T (Vibrio Alginolyticus Ferment Filtrate) — Polynesian atoll exopolysaccharide; stimulates desquamation, differentiation, transglutaminase; improves texture and tensile strength.

Dismutin PF (Superoxide Dismutase) — yeast-derived SOD; neutralizes superoxide radicals; protects cell membranes.

Phormistim G (Sea Water + Phormidium Persicinum Extract) — South African plankton; increases thioredoxin activity; reduces DNA damage.

Everlasting-ECO (Helichrysum Stoechas Extract) — polyphenol-rich; anti-aging; antioxidant.

Panthenol (Provitamin B5) — regenerative; soothing.

Amino Acid Complex (Alanine, Serine, Proline) — supports natural moisturizing factor and collagen signaling.

Full Ingredient List

Aqua/Water, Glycerin, Hydrogenated Polyisobutene, Polysilicone-11, Cetearyl Alcohol, Panthenol, PEG-100 Stearate, Maris Aqua, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Tetrahexyldecyl Ascorbate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Glucoside, Superoxide Dismutase, Pseudoalteromonas Ferment Extract, Sodium Metabisulfite, Caprylic/Capric Triglyceride, Hexylene Glycol, Vibrio Alginolyticus Ferment Filtrate, Tetrasodium EDTA, Xanthan Gum, Ethylhexylglycerin, Parfum, Tocopheryl Acetate, Palmitoyl Tripeptide-38, Laureth-12, Phormidium Persicinum Extract, Hydroxypropyl Cyclodextrin, Alanine, Serine, Proline, Helichrysum Stoechas Extract, Avena Sativa (Oat) Kernel Extract, Pentylene Glycol, Sodium Phosphate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Tromethamine, Caprylyl Glycol, Butylene Glycol, Phenoxyethanol.

Specifications

Product Details

Brand	Circadia by Dr. Pugliese
Product Type	Anti-aging antioxidant moisturizer
Skin Types	All Skin Types · Aging · Stressed Skin
Application	Morning and evening after cleansing and serums; smooth over face and neck; avoid eye area
Key Actives	BV-OSC (Tetrahexyldecyl Ascorbate), Matrixyl Synthe'6 (Palmitoyl Tripeptide-38), Exo-T, Dismutin PF (SOD), Phormistim G, Everlasting-ECO, Panthenol
Contains Fragrance	Yes — contains Parfum. Patch test recommended for fragrance sensitivities.
Sold By	Auréa Beauty — Authorized Circadia Retailer (myaurea.beauty)

FAQ

Common Questions

Everything you need to know about Circadia Phito-Pep 1.6 Antioxidant Lotion.

What is Circadia Phito-Pep 1.6 Antioxidant Lotion?

An anti-aging moisturizer that hydrates, strengthens the barrier, and reduces fine lines using BV-OSC (oil-soluble Vitamin C), Matrixyl Synthe'6, Exo-T, Dismutin PF (Superoxide Dismutase), and Phormistim G. Suitable for all skin types, particularly aging and stressed skin.

What is Matrixyl Synthe'6?

Matrixyl Synthe'6 (Palmitoyl Tripeptide-38) significantly increases synthesis of six major skin matrix components: collagen I, III, IV, fibronectin, hyaluronic acid, and laminin 5 — rebuilding skin structure from within to smooth wrinkles and restore firmness.

What is Exo-T and where does it come from?

Exo-T (Vibrio Alginolyticus Ferment Filtrate) is an exopolysaccharide produced by microorganisms living at the rims of Polynesian atolls. It stimulates desquamation, differentiation, and transglutaminase expression to regenerate skin and improve tensile strength, smoothness, and texture.

What is BV-OSC?

BV-OSC (Tetrahexyldecyl Ascorbate) is a highly stable, oil-soluble Vitamin C ester that penetrates deeply into the skin to reduce melanin synthesis and deliver antioxidant protection — without the oxidative instability of water-soluble Vitamin C.

How do I use Phito-Pep 1.6?

Morning and evening after cleansing and serums. Smooth over the face and neck, avoiding the eye area. Follow with SPF in the morning.

Is Auréa Beauty an authorized Circadia retailer?

Yes. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer. All products are 100% authentic and backed by the brand's quality guarantee.

Ideal For

Who Is This For?

All Skin TypesAging SkinStressed SkinFine Lines & WrinklesLoss of FirmnessRough TextureDull ComplexionDaily Moisturizer

For external use only. Avoid eye area. Contains Parfum — patch test recommended for fragrance sensitivities. If irritation occurs, discontinue use. Keep out of reach of children. Sold exclusively through authorized Circadia retailers. Auréa Beauty (myaurea.beauty) is an authorized Circadia professional skincare retailer.

Payment Protection + Pay Later Options
Easy 30-Day Returns

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GLOWING SKIN IS ALWAYS IN

Luxury That Loves Your Skin, Your Hair, and the Planet

Auréa Beauty stands for more than visible results—we stand for responsibility. We believe in derm-developed, cruelty-free, and sustainably sourced formulas.

✔ We're proudly woman-owned: created with heart, honesty, and intention.

✔ Real, medical-grade skincare and haircare you can actually trust—without fluff and false promises.

✔ We make self-care simple, personal, and powerful.

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Questions? We've got you!

Shipping & Returns

We ship within the US only.

1. Economy Shipping costs $11.99 and takes 5–8 business days.

2. Express Shipping costs $24.99 and takes 2–3 business days.

Yes, we accept returns within 30 days. Terms and conditions apply, see them here.

We accept a variety of payment methods including major credit cards (Visa, Mastercard, etc.), plus alternative payment options like Apple Pay, Shop Pay, and PayPal.

Once your order is placed and shipped, you will receive a confirmation email. Use the tracking information provided to follow delivery.

If you're missing tracking or have any concerns, please reach out to our customer support.

Products & Quality

Auréa Beauty is a proudly woman-owned online store offering premium, medical-grade skincare and advanced beauty devices.

All products are guaranteed authentic, dermatologist-recommended, sourced directly from trusted brands like Bio-Therapeutic, Circadia, GlyMed Plus, and TiZO.