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Lira Clinical PRO C4 Retinol Serum

Name: PRO C4 Retinol Serum
Brand: Lira Clinical
Availability: InStock
Rating: 5.0 (40 reviews)

$69.60

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Lira Clinical PRO C4 Retinol Serum

$69.60

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Lira Clinical · PRO Line · Retinol + Vitamin C Serum

PRO C4 Retinol Serum

1% Retinol paired with 4 forms of Vitamin C and 4 plant stem cells. Rejuvenates skin, reduces fine lines, wrinkles, and acne — a top-recommended starter retinol.

1% Retinol 4 Forms Vitamin C 4 Plant Stem Cells 🌙 PM Primary Use ☀️ Daily SPF Required ⚠️ Not for Pregnancy 1.69 fl oz

Made in USA

Cruelty-Free

Eco-Friendly Packaging

5.0★ · 40 Reviews

1%Retinol

4Forms Vitamin C

4Plant Stem Cells

5.0★40 Reviews

PMEvening Treatment

The Serum

Retinol Meets Quadruple Vitamin C. Gentle Enough to Start.

Rejuvenate skin with Vitamin C and Retinol serum. Contains 4 forms of Vitamin C, reduces fine lines, wrinkles, and acne. Key ingredients include Retinol, Vitamin C, Swiss Apple, Alpine Rose, Sea Fennel, Licorice Extract, and Olive Leaf Extract.

Peptide Tech

Vitamin C

1% Retinol

Plant Stem Cells

Hyaluronic Acid

Professional-Grade Formula

Retinol Starter-Friendly

Not for Eye Area

Esthetician Recommended

Fragrance Notice — Patch Test First

Science Ingredients

1% Retinol + Quadruple Vitamin C Complex

A gentle yet effective 1% retinol concentration makes this serum an ideal entry point for retinol newcomers and sensitive skin, while four distinct Vitamin C forms deliver layered antioxidant and brightening activity across multiple skin depths.

✓1% Retinol — keratolytic agent; skin rejuvenation and renewal
✓Tetrahexyldecyl Ascorbate (BV-OSC) — lipid-soluble Vitamin C; collagen synthesis; brightening
✓Ascorbyl Palmitate — fat-soluble Vitamin C; antioxidant, anti-inflammatory
✓Ascorbic Acid — pure Vitamin C; potent antioxidant and keratolytic
✓Citric Acid — natural AHA; brightening and pH optimization
✓Hyaluronic Acid (Sodium Hyaluronate Crosspolymer) — natural humectant; deep hydration
✓Ubiquinone (CoQ10) — powerful antioxidant; supports cellular energy and skin repair

Retinol + C4 Profile

1% RetinolKeratolytic · Skin rejuvenation

Tetrahexyldecyl AscorbateLipid-soluble Vit C · Collagen synthesis

Ascorbyl PalmitateFat-soluble Vit C · Antioxidant

Ascorbic AcidPure Vit C · Keratolytic

Citric AcidNatural AHA · Brightening

Hyaluronic AcidHumectant · Deep hydration

Ubiquinone (CoQ10)Antioxidant · Cellular repair

Nature Ingredients

4 Plant Stem Cells & Brightening Botanicals

A rare quartet of plant stem cells — Swiss Apple, Sea Fennel, Alpine Rose, and Edelweiss — provide multi-dimensional cellular repair, brightening, climate adaptation, and fibroblast stimulation, supported by anti-inflammatory botanical extracts.

✓Swiss Apple Plant Stem Cells — repairs and restores traumatized skin
✓Sea Fennel Plant Stem Cells (Crithmum Maritimum) — organic brightener
✓Alpine Rose Plant Stem Cells (Rhododendron Ferrugineum) — adapts skin to harsh climates
✓Edelweiss Plant Stem Cells (Leontopodium Alpinum) — stimulates healthy fibroblast activity
✓Licorice Extract (Dipotassium Glycyrrhizate) — anti-inflammatory, antioxidant, brightening
✓Olive Leaf Extract — anti-inflammatory; strengthens skin immunity; encourages hydration
✓Beet Root Extract (Beta Vulgaris) — anti-inflammatory, soothing
✓Green Tea Extract (Camellia Sinensis) — powerful antioxidant; inhibits melanosome transfer

Plant Stem Cell Profile

Swiss Apple Stem CellsRepairs & restores traumatized skin

Sea Fennel Stem CellsOrganic brightener

Alpine Rose Stem CellsClimate adaptation · Resilience

Edelweiss Stem CellsFibroblast stimulation

Licorice ExtractAnti-inflammatory · Brightening

Green Tea ExtractAntioxidant · Melanosome inhibitor

Olive Leaf ExtractSkin immunity · Hydration

Visible Results

Reduced Fine Lines

Diminished Wrinkles

Clearer Acne

Brighter Skin Tone

Smoother Texture

Improved Radiance

Cellular Renewal

Antioxidant Defense

How to Use PRO C4 Retinol Serum

Evening primary · 1–2 pumps · Follow with crème or oil · Not for eye area

1

Cleanse

Apply to freshly cleansed skin in the evening

2

Apply Serum

1–2 pumps pressed gently into skin. Avoid the eye area.

3

Moisturize

Follow with a Lira Clinical crème or oil to seal and hydrate

2×

Frequency

Up to twice daily depending on skin condition severity

☀️

Morning SPF

Broad-spectrum SPF 30+ every morning — essential with retinol use

Product Specifications

Brand	Lira Clinical
Line	PRO Line — Anti-Aging & Treatment
Product Type	Retinol + Vitamin C Serum
Size	1.69 fl oz · Pump Bottle
Usage Time	PM primary · Up to twice daily depending on severity
Application	1–2 pumps pressed into cleansed skin. Follow with crème or oil. Not for eye area.
Key Actives	1% Retinol, 4-Form Vitamin C (BV-OSC, Ascorbyl Palmitate, Ascorbic Acid, Citric Acid), Swiss Apple / Sea Fennel / Alpine Rose / Edelweiss Plant Stem Cells, Hyaluronic Acid, Licorice Extract, Olive Leaf Extract
Skin Concerns	Fine Lines, Wrinkles, Acne, Uneven Tone, Dullness, Hyperpigmentation, Texture
Innovative Tech	Peptide Tech · Vitamin C
Pregnancy	Not recommended during pregnancy or breastfeeding — contains Retinol. Consult physician.
Eye Area	Not to be used on the eye area
Fragrance Note	Contains Citrus Aurantium Dulcis (Orange) Peel Oil — patch test recommended for sensitive skin
SPF Requirement	Broad-spectrum SPF 30+ required daily — retinol increases photosensitivity
Origin	Made in USA
Certifications	Cruelty-Free · Eco-Friendly Packaging
Full Ingredients	Water (Aqua), Tetrahexyldecyl Ascorbate, Glycerin, Dimethicone, Cetearyl Olivate, Sorbitan Olivate, Sodium Hyaluronate Crosspolymer, Cetyl Palmitate, Sorbitan Palmitate, Malus Domestica Fruit Cell Culture, Lecithin, Imperata Cylindrica Root Extract, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Butylene Glycol, Yeast Polysaccharides, PPG-12/SMDI Copolymer, Cetearyl Alcohol, Retinol, Polysorbate 20, Camellia Sinensis Leaf Extract, Beta Vulgaris (Beet) Root Extract, Haberlea Rhodopensis Leaf Extract, Yeast Extract, Tocopherol, Ascorbyl Palmitate, Ascorbic Acid, Citric Acid, Xanthan Gum, Dipotassium Glycyrrhizate, Tocopheryl Acetate, Crithmum Maritimum Callus Culture Filtrate, Leontopodium Alpinum Meristem Cell Culture, Rhododendron Ferrugineum Leaf Cell Culture Extract, Isomalt, Lactic Acid, Disodium EDTA, Aloe Barbadensis Leaf Juice Powder, Ubiquinone, Olea Europaea (Olive) Leaf Extract, Citrus Aurantium Dulcis (Orange) Peel Oil.

Frequently Asked Questions

How do I use PRO C4 Retinol Serum?

Apply 1–2 pumps to cleansed skin in the evening. Follow with a Lira Clinical crème or oil. Can be used up to twice daily depending on skin condition severity. Not to be used on the eye area.

Is PRO C4 Retinol Serum suitable for retinol beginners?

Yes. At 1% retinol, PRO C4 Retinol Serum is an excellent entry point for first-time retinol users or those who have experienced irritation with higher-concentration formulas. Estheticians frequently recommend it as a starter retinol. Begin with evening use a few times per week and increase frequency as tolerated.

What are the 4 forms of Vitamin C in PRO C4 Retinol Serum?

PRO C4 Retinol Serum contains four distinct Vitamin C derivatives: Tetrahexyldecyl Ascorbate (BV-OSC), Ascorbyl Palmitate, Ascorbic Acid, and Citric Acid — delivering keratolytic, antioxidant, and anti-inflammatory benefits across multiple delivery pathways.

Is PRO C4 Retinol Serum safe during pregnancy?

PRO C4 Retinol Serum contains 1% Retinol. Retinol and retinoids are not recommended during pregnancy. Consult your physician before use if you are pregnant, planning to become pregnant, or breastfeeding.

Does PRO C4 Retinol Serum require daily SPF?

Yes. Retinol increases skin photosensitivity. Always apply a broad-spectrum SPF 30+ sunscreen every morning while using PRO C4 Retinol Serum, even if you apply the serum at night only.

Who Should Use This

Is PRO C4 Retinol Serum Right for You?

Retinol Beginners

First-time retinol users or those with past sensitivity — 1% concentration is the ideal gentle starting point

Anti-Aging Focus

Fine lines, wrinkles, and loss of firmness addressed through retinol-driven cellular renewal and Vitamin C collagen support

Acne-Prone Skin

Retinol's keratolytic action clears congestion while Vitamin C and botanicals address post-acne marks and texture

Brightening & Tone

Quadruple Vitamin C and Sea Fennel stem cells work together to brighten and even complexion over time

Not recommended during pregnancy or breastfeeding. Not for use on the eye area. Always apply SPF 30+ in the morning. Patch test if fragrance-sensitive.

Important Notices: PRO C4 Retinol Serum contains 1% Retinol — not recommended during pregnancy or breastfeeding. Consult your physician before use if pregnant or planning to become pregnant. Retinol increases photosensitivity — always apply a broad-spectrum SPF 30+ sunscreen every morning while using this product. Contains Citrus Aurantium Dulcis (Orange) Peel Oil; those with fragrance sensitivity should patch test before use. Not to be used on the eye area. For external use only. Discontinue if irritation occurs. Keep out of reach of children. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Auréa Beauty is an authorized retailer of Lira Clinical products.

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Shipping & Returns

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2. Express Shipping costs $24.99 and takes 2–3 business days.

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Products & Quality

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All products are guaranteed authentic, dermatologist-recommended, sourced directly from trusted brands like Bio-Therapeutic, Circadia, GlyMed Plus, and TiZO.